Institute News

Oct. 13, 2011
Dr. Jeff Chen started to collaborate with Dr.Josep Bassaganya-Riera at the Virginia Bioinformatics Institute on the projects with immunology and infectious disease.
May 01, 2011
iGECE investigators, Drs. Jeff Chen and Vladimir Makarov were just awarded a U.S. Army SBIR Phase I grant.
November 16, 2010
Dr. Jeff Chen was invited to give a seminar at the University of Mississippi Medical School.
July 13, 2010
iGECE officially exists as an organization approved by the Commonwealth of Virginia.

Infectious Disease Program

Clostridium difficile is a species of Gram-positive bacteria of the genus Clostridium that causes severe diarrhea and other intestinal disease when competing bacteria in the gut flora have been wiped out by antibiotics.

Helicobacter pylori is a Gram-negative, microaerophilic bacterium that can inhabit various areas of the stomach, particularly the antrum. It causes a chronic low-level inflammation of the stomach lining and is strongly linked to the development of duodenal and gastric ulcers and stomach cancer. Over 80 percent of individuals infected with the bacterium are asymptomatic. More than 50% of the world's population harbor H. pylori in their upper gastrointestinal tract. Infection is more prevalent in developing countries, and incidence is decreasing in Western countries. H. pylori's helix shape (from which the generic name is derived) is thought to have evolved to penetrate the mucoid lining of the stomach.

Gene Function Testing
on Infectious Disease Related and Immunology Genes