Cancer Systems Biology



Introduction
Known Perturbed Biological Pathways/Networks in Cancers
  1. PI3K-Akt-mTOR or RTK/RAS/PI3K Signaling Pathway, which is involved in the regulation of growth factor signals

  2. p53 Pathway, which is involved in response to DNA damage and cell death

  3. RB/E2F/the CDK/cyclin/CDK Inhibitor Pathway, which is involved in the regulation of cell division

  4. NF1 Ras Signaling Pathway

  5. Notch Signaling Pathway

  6. FOXM1 Signaling Pathway

  7. ErbB Signaling Pathway

  8. Wnt Signaling Pathway

  9. VEGF Pathway

  10. Defects in Homologous Recombination

Ongoing Pilot Data Mining on Some Cancers



First setup on May 30, 2012, last updated by Dr. Jeff Chen on June 4, 2012.