Dr. Xianfeng (Jeff) Chen
is the Full Member and Senior Investigator (Full Professor equivalent) of
iGECE, the Chief Scientific Officer
of the IFXworks Corporation, and the Executive Member of
ShengTing Group Corporation. Dr. Chen is
a world leading Bioinformatics and Computational Systems Biologist. Dr. Chen's scientific strengths include
genome annotation, network analysis, functional and comparative genomics, proteomics profiling, micro-array
transcription profiling, biological databases and data integration, biological system simulation and
modeling. During the course of his academic and industrial careers, Jeff was personally
responsible for assembly and analysis of over 170 microbial and 5 plant genomes, mouse
and human genomes, and also assembled human genome-scale protein-protein interaction
networks, as well as conducted research in target discovery for treatment of colon
cancer. Dr. Chen has authored over 50 publications in scholarly and professional
journals and over 20 U.S. and world patents. Dr. Chen was Assistant Professor at the
University of Virginia School of Medicine,
Research Investigator and Project Manager of Proteomics Cyber-infrastructure in the
NIH/NIAID National Biodefense
Program on Human Pathogens at the Virginia Bioinformatics Institute,
Principal Investigator (GS 14, Associate Professor equivalent)
and Bioinformatics Leader at the Federal Environmental Laboratory of the U.S. Army
and also a Bioinformatics Program Consultant to the Battelle Memorial Institute.
Prior to his academic career, Jeff worked for Prolexys Pharmaceuticals and
Companies. Jeff holds a Doctorate in Genetics and a Master (equivalent) in Computer Science, both from
Iowa State University, and a Master's degree in Biochemistry from the Chinese Academy of Sciences.
Selected Latest Relevant Publications and Patents
(Out of over 50 Publications and over 20 Patents) :
- Prateek Tripathi, Roel C. Rabara, Tanner J. Langum, Ashley K. Boken, Deena L. Rushton,
Darius D. Boomsma, Charles I. Rinerson, Jennifer Rabara, Neil R. Reese, Xianfeng Chen,
Jai S. Rohila, and Paul J. Rushton, 2012. The WRKY transcription factor family in Brachypodium
distachyon. BMC Genomics, 13:270 2012
- Deena Rushton, Prateek Tripathi, Roel Rabara, Lin Jun, Patricia Ringler, Ashley
Boken, Tanner Langum, Lucas Smidt, Darius Boomsma, Nicholas Emme, Xianfeng Chen,
John Finer, Qingxi She, Paul Rushton, 2011. WRKY transcription factors: key components in
abscisic acid signaling.
Plant Biotechnology Journal, (2012) 10, pp. 2–11 (doi: 10.1111/j.1467-7652.2011.00634.x).
- Xianfeng Chen, Kurt A. Gust, Mitchell S. Wilbanks, Edward J. Perkins, Natalie
D. Baker, Don Pham, Leona Scanlan, and Chris Vulpe, 2010. Supercomputer Assembly and
Annotation of Transcriptomes for Assessing Impact of Army Stressors on Ecological
Receptors. 27th Army Science Conference Proceedings, 2010, Paper No.: LP-013.
- Carlos M. Hernandez-Garcia, Robert A. Bouchard, Paul J. Rushton, Michelle L. Jones,
Xianfeng Chen, Michael P. Timko, and John J. Finer, 2010. Rapid validation of 20
different soybean (Glycine max) promoters in transiently- and stably-transformed
BMC Plant Biology, 2010, 10:237 .
- Michael P. Timko, Paul J. Rushton, Thomas W. Laudeman, Marta T. Bokoviec, Edmond
Chipumuro, Foo Cheung, Christopher D. Town, and Xianfeng Chen, 2008. Sequencing
and Analysis of the Gene-Rich Space of Cowpea. BMC Genomics,
2008, 9:103 .
- Paul J. Rushton, Marta T. Bokowiec, Thomas W. Laudeman, Jennifer F. Brannock,
Xianfeng Chen, and Michael P. Timko, 2008. TOBFAC: The Database of Tobacco
Transcription Factors. BMC Bioinformatics,
- Paul J. Rushton, Marta T. Bokowiec, Shengcheng Han, Hongbo Zhang , Jennifer F.
Brannock, Thomas W. Laudeman, Xianfeng Chen, and Michael P. Timko, 2008.
Bioinformatics Analysis on Tobacco Transcription Factors: Novel Insights into Transcriptional
Regulation in the Solanaceae.
Plant Physiology, 2008, 147:280-295.
- Xianfeng Chen, Thomas W. Laudeman, Paul J. Rushton, Thomas A. Spraggins, and
Michael P. Timko, 2007. CGKB: An Annotation Knowledge Base for Cowpea (Vigna unguiculata L.)
Methylation Filtered Genomic Genespace Sequences.
- Guoqing Lu, Liying Jiang, Resa M. Kotalik, Thaine W. Rowley, Luwen Zhang,
Xianfeng Chen, and Etsuko N. Moriyama, 2006. GenomeBlast: A Web Tool for Small
BMC Bioinformatics, 2006, 7 (Suppl 4):S18.
- Xianfeng Chen et al. (co-authored with about 20 co-inventors), 2009. Sequence-determined DNA fragments and
corresponding polypeptides encoded therapy. Patent Application Number:
- Xianfeng Chen et al. (co-authored with about 5 co-inventors), 2008.
Expression of microbial proteins in plants for production of plants with improved properties. United
States Patent in Bioinformatics and Biotechnology. Publication Number:
10369493 (US 2003/0233675 A1).
- Xianfeng Chen et al (co-authored with about 10 inventors), 2008. Transgenic
Plants with Enhanced Agronomic Traits. International Patent in Bioinformatics and
Biotechnology. Publication Number: WO/2008/021543.